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SPOT-Light CISH Centromere Detection Kit   84-9248   1 kit

Full Product Description The SPOT-Light® CISH (Chromogenic In Situ Hybridization) Centromere Detection kit will detect biotin-labeled probes, especially optimized for our

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SPOT-Light® HER2 CISH Kit   84-0150   1 kit

All US customers require certification prior to purchasing this product (visit invitrogen.com⁄her2cishcert). In the US, this product is exclusively distributed by Biocare

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SPoT-Light Chromosome X Centromeric Probe   84-1100   0.4 ml

The Chromosome X Centromeric Probe may be used to assist in the diagnosis of androgen receptor (AR) gene amplification and sex determination. Use with: Spot-Light® CISH

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SPoT-Light Chromosome 18 Centromeric Probe   84-1200   0.4 ml

Aneuploidy of chromosome 18 is associated with the development of colorectal carcinoma. The detection of multiple copy numbers of chromosome 18 is useful information for the ISH

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SPoT-Light Chromosome Y Probe   84-1600   0.4 ml

Chromosome Y probe alone or with chromosome X centromeric probe may be used for sex determination in prenatal diagnosis as well as for monitoring patients after sex mismatch bone

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SPoT-Light Cyclin D1 Amplification Probe   84-1900   0.4 ml

Cyclin D1 (CCND1) gene is a 15 kb gene located at chromosome 11q13. Cyclin D1 is a key regulator of the cell cycle especially for G1 to S phase progression. Cyclin D1 amplification

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SPOT-Light Chromosome 18q Deletion Probe   84-2800   0.4 ml

Full Product Description Loss of chromosome 18q is frequently observed in colorectal carcinoma and head and neck carcinoma, and is associated with poor outcome. Chromosome 18q

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SPoT-Light Chromosome 3 Centromeric Probe   84-1500   0.4 ml

Monosomy of chromosome 3 has been observed in renal cell carcinoma (RCC) and uveal melanoma. In addition, studies have shown that trisomy 3 may be a common chromosomal abnormality

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SPoT-Light Chromosome 7 Centromeric Probe   84-0800   0.4 ml

A change in copy number of chromosome 7 (aneuploidy or polysomy) is commonly observed in solid tumors (such as prostate cancer, renal tumor, and bladder cancer), hematological

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SPoT-Light Chromosome 19q Deletion Probe   84-2600   0.4 ml

Chromosome 19q deletion occurs in 75% oligoendrofliomas, 45% mixed oligoastrocytomas, and 40% astrocytomas. Loss of an entire copy of 19q is more commonly found in oligodendroglial

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SPoT-Light EGFR Probe   84-1300   0.4 ml

EGFr gene amplification has been associated with 40% of glioblastoma multiforme cases, 8-20% of head and neck cancers, 8-14% of esophageal cancers, 3-6% of gastric cancers, and 2%

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SPoT-Light Chromosome 10 Centrometric Probe   84-2200   0.4 ml

Monosomy of chromosome 10 has been observed in malignant gliomas and correlates with histological grade. Loss of chromosome 10 appears to be an earlier event than gain of a

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SPoT-Light N-Myc Probe   84-0400   0.4 ml

Amplification of Myc gene commonly occurs in a wide range of tumors. N-Myc, which is primarily expressed in neuronal cells during embryogenesis, is amplified in neuroblastomas and

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SPoT-Light Tissue Pretreatment Kit   00-8401   1 kit

For Enzyme and Heat Pretreatment of FFPE Tissue prior to CISH.

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SPOT-Light Bone Marrow - Blood Smear CISH Detection Kit   84-9214   1 kit

Full Product Description The Bone Marrow⁄Blood Smear CISH Detection kit will detect digoxigenin-labeled and biotin-lableled probes on bone marrow and blood smear samples.

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SPOT-Light Chromosome 8 Centromere Probe   84-0900   0.4 ml

Full Product Description Change in copy number of chromosome 8 (aneuploidy or polysomy) is commonly observed in ovarian cancer, clear cell sarcomas, bladder cancers and some

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SPoT-Light CISH Detection Kit   84-9243   1 kit

This CISH kit will detect digoxigenin (DIG)-labeled probes. It can be used only for CISH. Applications: CISH (Chromogenic In Situ Hybridization)

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SPoT-Light Chromosome 17 Centromeric Probe   84-0500   0.4 ml

Chromosome 17 Centromeric Probe may be useful in assisting in the evaluation of results from other ISH assays that detect gene amplification markers on chromosome 17 such as

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SPoT-Light Topoisomerase II α Probe   84-0600   0.4 ml

DNA-topoisomerase II (Topo II or Top2) is a multifunctional nuclear enzyme required during DNA replication, chromosome disjunction at mitosis, and other DNA-related activities

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HER2 CISH Certification Combo Kit   84-0160   1 kit

For HER2 CISH certification of US customers only. US customers must complete the online tutorial at www.invitrogen.com/her2cishcert prior to ordering this product. /> The

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SPoT-Light SYT Translocation Probe Pair   84-2500   0.4 ml

The SYT gene maps to chromosome band 18q11.2 Chromosomal translocation of SYT gene occurs in up to 95% synovial sarcomas (SS) and characterized by t(X;18)(p11.2;q11.2). The main

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SPOT-Light Chromosome 1p36 Deletion Probe   84-3000   0.4 ml

Full Product Description Loss of chromosome 1p36 and 19q is frequently observed in oligodendroglioma, and is also used as a prognostic marker. Use with: CISH Polymer Detection

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SPOT-Light Chromosome 4q12 Deletion Probe   84-3100   0.4 ml

Full Product Description This Chromosome 4q12 Deletion Probe specifically targets the interstitial region between FIP1L1-PDGFRA genes on chromosome 4q12 and may be useful in the

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SPoT-Light EWS Translocation Probe Pair   84-0300   0.4 ml

EWS translocations are found in the soft tissue tumors which are Ewing tumors (ET), including Ewing sarcoma of bones and soft tissues (ES), and peripheral primitive neuroectodermal

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SPOT-Light CISH Polymer Detection Kit   84-9246   1 kit

This CISH detection kit will detect digoxigenin (DIG)-labeled probes. It can be used only for CISH. Since the kit uses a polymerized HRP⁄DAB detection system to localize DIG

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