Full Product Description The SPOT-Light® CISH (Chromogenic In Situ Hybridization) Centromere Detection kit will detect biotin-labeled probes, especially optimized for our
All US customers require certification prior to purchasing this product (visit invitrogen.com⁄her2cishcert). In the US, this product is exclusively distributed by Biocare
The Chromosome X Centromeric Probe may be used to assist in the diagnosis of androgen receptor (AR) gene amplification and sex determination. Use with: Spot-Light® CISH
Aneuploidy of chromosome 18 is associated with the development of colorectal carcinoma. The detection of multiple copy numbers of chromosome 18 is useful information for the ISH
Chromosome Y probe alone or with chromosome X centromeric probe may be used for sex determination in prenatal diagnosis as well as for monitoring patients after sex mismatch bone
Cyclin D1 (CCND1) gene is a 15 kb gene located at chromosome 11q13. Cyclin D1 is a key regulator of the cell cycle especially for G1 to S phase progression. Cyclin D1 amplification
Full Product Description Loss of chromosome 18q is frequently observed in colorectal carcinoma and head and neck carcinoma, and is associated with poor outcome. Chromosome 18q
Monosomy of chromosome 3 has been observed in renal cell carcinoma (RCC) and uveal melanoma. In addition, studies have shown that trisomy 3 may be a common chromosomal abnormality
A change in copy number of chromosome 7 (aneuploidy or polysomy) is commonly observed in solid tumors (such as prostate cancer, renal tumor, and bladder cancer), hematological
Chromosome 19q deletion occurs in 75% oligoendrofliomas, 45% mixed oligoastrocytomas, and 40% astrocytomas. Loss of an entire copy of 19q is more commonly found in oligodendroglial
EGFr gene amplification has been associated with 40% of glioblastoma multiforme cases, 8-20% of head and neck cancers, 8-14% of esophageal cancers, 3-6% of gastric cancers, and 2%
Monosomy of chromosome 10 has been observed in malignant gliomas and correlates with histological grade. Loss of chromosome 10 appears to be an earlier event than gain of a
Amplification of Myc gene commonly occurs in a wide range of tumors. N-Myc, which is primarily expressed in neuronal cells during embryogenesis, is amplified in neuroblastomas and
For Enzyme and Heat Pretreatment of FFPE Tissue prior to CISH.
Full Product Description The Bone Marrow⁄Blood Smear CISH Detection kit will detect digoxigenin-labeled and biotin-lableled probes on bone marrow and blood smear samples.
Full Product Description Change in copy number of chromosome 8 (aneuploidy or polysomy) is commonly observed in ovarian cancer, clear cell sarcomas, bladder cancers and some
This CISH kit will detect digoxigenin (DIG)-labeled probes. It can be used only for CISH. Applications: CISH (Chromogenic In Situ Hybridization)
Chromosome 17 Centromeric Probe may be useful in assisting in the evaluation of results from other ISH assays that detect gene amplification markers on chromosome 17 such as
DNA-topoisomerase II (Topo II or Top2) is a multifunctional nuclear enzyme required during DNA replication, chromosome disjunction at mitosis, and other DNA-related activities
For HER2 CISH certification of US customers only. US customers must complete the online tutorial at www.invitrogen.com/her2cishcert prior to ordering this product. /> The
The SYT gene maps to chromosome band 18q11.2 Chromosomal translocation of SYT gene occurs in up to 95% synovial sarcomas (SS) and characterized by t(X;18)(p11.2;q11.2). The main
Full Product Description Loss of chromosome 1p36 and 19q is frequently observed in oligodendroglioma, and is also used as a prognostic marker. Use with: CISH Polymer Detection
Full Product Description This Chromosome 4q12 Deletion Probe specifically targets the interstitial region between FIP1L1-PDGFRA genes on chromosome 4q12 and may be useful in the
EWS translocations are found in the soft tissue tumors which are Ewing tumors (ET), including Ewing sarcoma of bones and soft tissues (ES), and peripheral primitive neuroectodermal
This CISH detection kit will detect digoxigenin (DIG)-labeled probes. It can be used only for CISH. Since the kit uses a polymerized HRP⁄DAB detection system to localize DIG